This regional report, Comprehensive sexuality education: Key considerations for implementation and scaling up in West and Central Africa, documents promising practices and lessons learned, from four West African countries (Benin, Côte d’Ivoire, Senegal and Togo), and proposes key recommendations to be shared with all countries in the region. The UNFPA West and Central Africa Regional Office (WCARO) reiterates its full support to governments and other partners for developing and scaling up CSE programmes in all countries throughout the region. This support will enable young people throughout the region to develop their health and well-being with dignity.